Clinical Data Management + Operations

Avoiding Endpoint Integrity Issues

Early detection of COA data quality issues kept a pivotal trial on track.
The challenge

Data anomalies at key sites went undetected until they jeopardized endpoint validity.

The team noticed that endpoint measures from several sites appeared inconsistent, and traditional systems failed to catch the issues. Weeks later, the team confirmed that invalid, zero-valued COA scores were distorting results and threatening endpoint integrity.

Our Solution

Vivo’s pattern recognition flagged invalid measures early, enabling rapid intervention and protecting trial outcomes.

With Vivo, the team was able to proactively detect outliers, null values, and data shifts tied to specific sites. Teams were notified early, issues were reviewed, and site training was adjusted to preserve data integrity.

OUR Product
Vivo, the solution for the overwhelming amount of data in clinical trials
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