Clinical Data Management + Operations
Avoiding Endpoint Integrity Issues
Early detection of COA data quality issues kept a pivotal trial on track.

The team noticed that endpoint measures from several sites appeared inconsistent, and traditional systems failed to catch the issues. Weeks later, the team confirmed that invalid, zero-valued COA scores were distorting results and threatening endpoint integrity.
With Vivo, the team was able to proactively detect outliers, null values, and data shifts tied to specific sites. Teams were notified early, issues were reviewed, and site training was adjusted to preserve data integrity.